German government re-thinking ban on human cloning

Clearly recognizing that extreme differences in position still exist, the government has called for reconsidering its position on human cloning for purposes of stem cell research.Seeing that many other countries are changing their attitudes–including England’s latest move to open research for a year–they are concerned about losing residents. “Simitis warned that a type of ‘bio tourism’ might develop within the EU and that German researchers would immigrate to Great Britain if Germany did not rethink its stance.”

Just as women began shopping for the right cleric–meaning the cleric with the ‘right’ attitude about it–when birth control became easily available many years ago and yet was banned by the Catholic Church, this fear of people going elsewhere to get more advanced medical care is not unrealistic.

Biomed in Silicon Valley pulling big VC dollars

Biomed has surpassed software for the first time in attracting VC money–and it’s filling the gap, at least partially, that the dot.com bust created. In the last year high-tech investors have switched to supporting biotechnology and medical device companies — to the tune $241.7 billion in Silicon Valley alone. Biomedical companies create jobs and spending that can help smooth out a region’s rough spots.

“The Bay Area’s biomedical sector is getting one of every four venture capital dollars — compared with one out of 16 in the year 2000’s frenzy of high-tech investment.”

The article goes on to say that rate of payback is speeding up, and bio investors don’t have to quite so patient anymore. No wonder everybody’s in such a race for bio-tech-med favor

Business use discovered for DNA analysis tool

Gotta post this here, too. I put in Blog for Business because it’s such good news for business people. A technique for reading DNA has now been applied to reading and isolating spam emails.This is a sign of things to come.

“Instead of chains of characters representing DNA sequences, the research group fed the algorithm 65,000 examples of known spam. Each email was treated as a long, DNA-like chain of characters. Teiresias identified six million recurring patterns in this collection, such as ‘Viagra.’

“Each pattern represented a common sequence of letters and numbers that had appeared in more than one unsolicited message. The researchers then ran a collection of known non-spam (dubbed “ham”) through the same process, and removed the patterns that occurred in both groups.”

Rate of error–deleting a genuine email–was 1 in 6000. How much time do you waste deleting emails? Is it worth that risk?

I’m sure that as scientists you have long noticed that patterns exist everywhere we look. Here’s another illustration of how a technique from one discipline can have direct transferrability to another–if you only jog your thinking enough.

Cloning for mad-cow-disease-resistant calves gets funding in Korea

Using the in vivo technique which is conducted in natural environments (as opposed to in vitro which are done in labs) the Korean scientist who cloned the first human embryo from stem cells early this year has received big funding for the experiment using surrogate cow mothers, some of which he’s reportedly hand picked. And there’s more.

“The Korea Research Institute of Bioscience and Biotechnology (KRIBB) yesterday said it would pour 7.7 billion won [if my calculations are correct that’s about US$6.65 million] to build the Korea National Primate Research Center by next year. The center, which the KRIBB plans to complete midway through next year, will focus on studying stem cells to produce next-generation medicines based on advanced biotechnology.

Earlier last month, Kyonggi Province and the Ministry of Science and Technology decided to shell out 7.8 billion won to set up a facility for miniature pigs, which can provide human organs for transplants.”

Hwang’s successful cloning may have been the beginning of a new era–unrestricted research that uses stem cells to find treatments for many chronic diseases. I personally know two people who have overcome two different almost-always fatal varieties of cancer by having had stem cell implants using their own stem cells. My guess is investors all over the world are already dumping lots of money into this research–wherever it’s being done.

Stem cell patches can grow new heart tissue

Using a patient’s own stem cells, scientistis can replace certain areas of damaged heart tissue. Using bone marrow taken from the hip. doctors isolate stem cells, and in a new study, they plan to inject 30 million of them into one patient’s heart (the 6th in the country to receive this treatment). Chief of Cardiology at the Texas Heart Institute says some of the stem cells become new blood vessels, some new heart muscle cells. “Other cells fuse, latch onto existent heart muscle cells in sort of a blob and they exchange nuclear material.” Doctors believe this fusion process allows the injected cell to rescue the injured cell. In Tokyo researchers pulled stem cells from a leg muscle and grew a cardiac patch.

This is great news for potential heart transplant patients who may eventually not have to undergo the invasive procedure. But for those with other types of heart disease, such as problems with valves, this work gives hope that one day their own stem cells might help heal or even replace the dysfunctional parts.

Wow. This truly gives new meaning to the old admonition “Heal thyself”…

Indian experts say radiation from mobile phone towers is bad

Indian health officials declare waves and radiations from mobile phone towers potentially dangerous to the hearts and/or brains of those in the vicinity. Officials from India’s Health Services %28DHS%29 and head of the Neurology Department at PGI%2C raised the safety issue at a public meeting that included, among others, the country’s Air Force and its Department of Telecom %28DoT%29.

The neurologist said that the horizontal area within 30 meters (about 100 ft.) of the towers is not safe, and that protective gear must be worn by anyone going within 3 meters (about 10 feet). Some U.S. scientists disagree: Here’s a report on ElectroMagnetic Fields and Human Health by a professor of Radiation Oncology at the Medical College of Wisconsin.

Where does the truth lie? Like everything we discover and put to good use (who could live without cell phones nowadays?), there are often hidden costs against life that we a) don’t catch at all, or b) seriously underestimate.

Walking the middle line and keeping the balance is all we can ask of our scientists, inventors and investigators.

Partnership a good model for entrepreneurs

Quinton Cardiology Systems will sell Cardiac Science’s Professional Model AED Under Burdick Brand Name A company with a powerful distribution system agrees to sell another company’s product–a good partnership idea. Mutually beneficial collaboration–rather than every entrepreneur for herself–is surely a strong way to lower costs, increase efficiency, and gain greater market share–all the stuff all companies want to do.

This new model, CardioVive DM(TM), lets medical professionals see the patient’s heart rhythm on a built-in high resolution color electrocardiogram (ECG) display. Professional users can deliver defibrillation shocks either semi-automatically or manually if the patient has a sudden cardiac arrest. Other cool features include “continuous cardiac monitoring capability via an ECG patient cable, multiple rescue data storage, clear and comprehensive AED and CPR voice prompts, infrared data transfer and optional rechargeable battery.”

Voice prompts–I like that–that’s a trend, I’ll wager. Tech writers in future will be writing scripts instead of long, stuffy sets of documentation.

Anemia predicts poor outcomes for heart interventions

“…having anemia was associated with a higher rate of major cardiac events within 30 days and a longer hospital stay. After considering factors that increase the mortality risk, such as kidney failure and diabete, anemia was still a significant predictor of 1-year mortality.Whether patients had a history of angina, chest pain or heart attack, anemia was still a culprit in worse survival rates. Conclusion: overall treatment strategy ought to take anemia into consideration, especially if it’s severe.

Once again (see earlier post) it’s good to know that scientists are focusing on research that will help people live longer, not just survive their heart attacks. Otherwise, what is the point, really?

Partners developing device to vaporize liquid for respiratory care

Vapore and PARI Partner to Develop Medical Device “Vapore has developed a new breakthrough method of liquid vaporization called the capillary force vaporizer (CFV), a compact, heat-powered disc that generates a powerful jet of pressurized vapor from un-pressurized liquid–with no moving parts. PARI’s medical devices will integrate Vapore’s CFV to provide a compact precision vapor generator.” The CFV combines capillary force and phase transition–two ‘natural phenomena’–to produce a controllable flow of vapor that’s simple to deliver and doesn’t rely on environmentally harmful aerosol propellants. (Never fear, you other non-scientific readers out there. I have a question in to an official medical source to find out what the heck “phase transition” means–and while I was at it I thought I’d ask what the technical meaning of capillary force is–we all know what capillaries are but it’s not absolutely clear what the ‘force’ is about).

First, the hair care people figured out how to quit using those bad spray propellants a long time ago. And then the HVAC manufacturers got rid of freon in air conditioners quite a few years ago. It’s really good news to hear that investigators have found a way to deliver medicine to a person’s lungs that also doesn’t offend the environment–or the person’s lungs.

US/China Pharmaceutical parntership to develop Septic Shock Drug

Medinox and PUMC Pharmaceutical Company Agree to Collaborate on Developing NOX-100 Septic Shock Drug in China and South Korea: Estimated number of septic shock patients is 600,000 in the US and 2 million in China per year; half of those patients die.

“The results of this trial in patients with severe septic shock indicate a beneficial effect for NOX-100 with a possible survival advantage and an excellent safety profile.” Using NO neutralizers to remove dangerously overproduced NO from inflamed tissues yet not affecting the low levels of NO needed for normal ongoing organ functions is a novel approach to therapy.

Just musing here. NO (nitric oxide) plays a big part in inflammation–yet it is an element we need in our bodies. This seems to be a profile for lots of human diseases. Something that’s natural and necessary gets out of control. Actually that sounds like a formula that could fit dysfunction at several levels…physiological, mental and business-wise.

Looking at how bioscience news affects business, higher education, government – and you and me